Description

Diethyl 10-Undecyn-1-Ylphosphonate, 95% is a high-purity, functionalized phosphonate ester featuring a terminal alkyne group. This unique bifunctional structure makes it a valuable advanced synthetic intermediate for constructing complex molecules via click chemistry and organophosphorus chemistry. It is primarily utilized by pharmaceutical researchers and specialty chemical manufacturers in the development of active pharmaceutical ingredients (APIs), agrochemicals, and novel materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Click Chemistry Reagent: The terminal alkyne enables efficient, selective Huisgen 1,3-dipolar cycloaddition (copper-catalyzed azide-alkyne cycloaddition, CuAAC) for bioconjugation and polymer functionalization.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging the phosphonate moiety for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for phosphorus-containing ligands used in homogeneous catalysis.
• Material Science: Incorporated into polymers and surfaces to modify properties such as adhesion, flame retardancy, or biocompatibility.
• Organic Synthesis: Employed in Horner-Wadsworth-Emmons (HWE) olefination reactions to introduce elongated alkene chains with precision.

Basic Information

Product Name	Diethyl 10-Undecyn-1-Ylphosphonate, 95%
CAS No.	1242248-76-5
Molecular Formula	C₁₅H₂₇O₃P
Molecular Weight	286.35 g/mol
Synonyms	Diethyl (10-undecyn-1-yl)phosphonate; Diethyl 10-undecynylphosphonate; (10-Undecyn-1-yl)phosphonic acid diethyl ester; 10-Undecyn-1-ylphosphonic acid diethyl ester; Diethyl (10-undecynyl)phosphonate; Phosphonic acid, (10-undecyn-1-yl)-, diethyl ester; Undecynylphosphonic acid diethyl ester
EINECS	Contact for details

Quality Control

Our Diethyl 10-Undecyn-1-Ylphosphonate is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure the specified purity and identity. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, supporting your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.