Description

Methyl 3-Bromo-4-(((Trifluoromethyl)Sulfonyl)-Oxy)-5-(Trimethylsilyl)Benzoate is a high-value, multi-functional synthetic intermediate designed for advanced chemical synthesis. This compound is engineered to serve as a versatile building block, offering unique reactivity for constructing complex molecular architectures. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those requiring trifluoromethyl and silyl-protected phenol functionalities.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the bromo and sulfonate ester groups enable strategic coupling reactions.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the reactive bromine atom.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds or probes for studying biological mechanisms and pathways.
• Custom Synthesis & Contract Manufacturing: A critical component for fine chemical manufacturers offering bespoke synthesis services to clients in life sciences.

Basic Information

Item	Details
Product Name	Methyl 3-Bromo-4-(((Trifluoromethyl)Sulfonyl)-Oxy)-5-(Trimethylsilyl)Benzoate
CAS No.	1242069-33-5
Molecular Formula	C12H12BrF3O5SSi
Molecular Weight	449.25 g/mol
Synonyms	Methyl 3-bromo-4-(((trifluoromethyl)sulfonyl)oxy)-5-(trimethylsilyl)benzoate; 3-Bromo-4-(((trifluoromethyl)sulfonyl)oxy)-5-(trimethylsilyl)benzoic acid methyl ester; Methyl 3-bromo-5-(trimethylsilyl)-4-((trifluoromethyl)sulfonyloxy)benzoate; 4-(Trifluoromethanesulfonyloxy)-3-bromo-5-(trimethylsilyl)benzoic acid methyl ester; Benzoic acid, 3-bromo-4-(((trifluoromethyl)sulfonyl)oxy)-5-(trimethylsilyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Bromo-4-(((Trifluoromethyl)Sulfonyl)-Oxy)-5-(Trimethylsilyl)Benzoate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical specifications are available upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.