Description

5-Bromo-2-(2,2-difluoroethoxy)-3-ethoxypyridine is a high-purity, multi-functional pyridine derivative designed for advanced chemical synthesis. This compound serves as a critical building block in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is essential for researchers and manufacturers seeking to incorporate a brominated, difluoroethoxy-substituted pyridine core into their target structures, enabling the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the pyridine scaffold and halogen/ether substitutions contribute to biological activity.
• Material Science: Serves as a monomer or functional additive in the synthesis of specialty polymers, liquid crystals, and electronic materials.
• Chemical Synthesis: Acts as a versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitutions due to the reactive bromine atom.
• Life Science Research: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a probe molecule in biochemical assays.

Basic Information

Product Name	5-Bromo-2-(2,2-difluoroethoxy)-3-ethoxypyridine
CAS No.	1241752-36-2
Molecular Formula	C9H10BrF2NO2
Molecular Weight	282.08 g/mol
Synonyms	5-Bromo-3-ethoxy-2-(2,2-difluoroethoxy)pyridine; 2-(2,2-Difluoroethoxy)-5-bromo-3-ethoxypyridine; 3-Ethoxy-5-bromo-2-(2,2-difluoroethoxy)pyridine; Pyridine, 5-bromo-2-(2,2-difluoroethoxy)-3-ethoxy-; 1241752-36-2; 5-Br-2-(2,2-F2EtO)-3-EtO-Pyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(2,2-difluoroethoxy)-3-ethoxypyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and current industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥97.0% (Area %)
Purity (HPLC)	≥98.0%
Related Substances (HPLC)	Individual impurity ≤1.0%; Total impurities ≤2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.