Description

5-Bromo-2-isopropoxy-3-methoxypyridine is a high-purity, multi-functional pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of bromine and alkoxy substituents, which enable precise functionalization and scaffold diversification for complex molecule construction. This intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a versatile scaffold for constructing sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological pathways and target engagement.
• Custom Synthesis and Scale-Up: A foundational unit for contract research and manufacturing organizations (CROs/CMOs) performing custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	5-Bromo-2-isopropoxy-3-methoxypyridine
CAS No.	1241752-33-9
Molecular Formula	C9H12BrNO2
Molecular Weight	246.10 g/mol
Synonyms	3-Methoxy-5-bromo-2-isopropoxypyridine; 2-Isopropoxy-3-methoxy-5-bromopyridine; 5-Bromo-3-methoxy-2-(propan-2-yloxy)pyridine; 5-Bromo-2-(1-methylethoxy)-3-methoxypyridine; Pyridine, 5-bromo-2-(1-methylethoxy)-3-methoxy-; 1241752-33-9
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-isopropoxy-3-methoxypyridine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.