Description

5-Chloro-3-Iodo-1-(4-Methylbenzenesulfonyl)-1H-Pyrrolo[2,3-B]Pyridine is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for medicinal chemistry research and development, serving as a versatile intermediate in the creation of novel pharmaceutical candidates. It is primarily utilized by R&D scientists and process chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients with complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Agrochemical Development: Serves as a building block for creating new crop protection compounds with specific modes of action.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.
• Fine Chemical Synthesis: Enables the construction of complex, functionalized pyrrolopyridine scaffolds for specialty chemical applications.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis and scale-up projects.

Basic Information

Product Name	5-Chloro-3-Iodo-1-(4-Methylbenzenesulfonyl)-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1241675-24-0
Molecular Formula	C14H10ClIN2O2S
Molecular Weight	432.66 g/mol
Synonyms	1H-Pyrrolo[2,3-b]pyridine, 5-chloro-3-iodo-1-[(4-methylphenyl)sulfonyl]-; 5-Chloro-3-iodo-1-tosyl-1H-pyrrolo[2,3-b]pyridine; 5-Chloro-3-iodo-1-(p-toluenesulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1-(4-Methylbenzenesulfonyl)-5-chloro-3-iodo-1H-pyrrolo[2,3-b]pyridine; 5-Chloro-3-iodo-1-tosyl-1H-pyrrolo[2,3-b]pyridine; Tosyl-protected 5-chloro-3-iodo-7-azaindole
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-Iodo-1-(4-Methylbenzenesulfonyl)-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.