Description

5-(2-Fluorophenyl)-1H-Pyrrole-3-Carboxylic Acid Methyl Ester is a high-value fluorinated pyrrole derivative, a crucial heterocyclic building block in modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecular architectures, particularly for applications demanding specific electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, serving as a key intermediate in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the research and development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Used in the synthesis of advanced crop protection agents, where the fluorophenyl-pyrrole scaffold can contribute to enhanced biological activity and environmental stability.
• Material Science Research: Serves as a precursor for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its conjugated system.
• Chemical Biology Probes: Employed in the design and synthesis of fluorescent tags and molecular probes for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring functionalized pyrrole cores for specialized applications.

Basic Information

Product Name	5-(2-Fluorophenyl)-1H-Pyrrole-3-Carboxylic Acid Methyl Ester
CAS No.	1240949-59-0
Molecular Formula	C12H10FNO2
Molecular Weight	219.21 g/mol
Synonyms	Methyl 5-(2-fluorophenyl)-1H-pyrrole-3-carboxylate; 1H-Pyrrole-3-carboxylic acid, 5-(2-fluorophenyl)-, methyl ester; 5-(2-Fluorophenyl)-1H-pyrrole-3-carboxylic acid methyl ester; 2-Fluorophenyl pyrrole ester; Fluorophenyl pyrrole carboxylate methyl ester
EINECS	Contact for details

Quality Control

Our 5-(2-Fluorophenyl)-1H-Pyrrole-3-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.