Description

3-Pyridinecarbonitrile, 4-Bromo-2-Fluoro- is a high-purity, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular architecture, which allows for selective functionalization at multiple reactive sites, enabling the construction of complex heterocyclic systems. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology Probes: Utilized as a building block for synthesizing molecular probes and tags for studying biological systems and drug-target interactions.
• Custom Synthesis and Scale-up: A fundamental starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	3-Pyridinecarbonitrile, 4-Bromo-2-Fluoro-
CAS No.	1240620-65-8
Molecular Formula	C6H2BrFN2
Molecular Weight	200.99 g/mol
Synonyms	4-Bromo-2-fluoronicotinonitrile; 4-Bromo-2-fluoropyridine-3-carbonitrile; 2-Fluoro-4-bromonicotinonitrile; 3-Cyano-4-bromo-2-fluoropyridine; 4-Bromo-2-fluoro-3-pyridinecarbonitrile; 1240620-65-8; 4-Bromo-2-fluoro-3-cyanopyridine
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridinecarbonitrile, 4-Bromo-2-Fluoro- undergoes rigorous analytical testing to ensure it meets the high standards required for research and development. Our quality assurance protocols are designed to guarantee batch-to-batch consistency, purity, and identity. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Water Content (KF)	< 1.0%
Residue on Ignition	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.