Description

6-Cyclobutylpicolinonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its cyclobutyl-substituted picolinonitrile core structure. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel small-molecule drugs.
• Medicinal Chemistry Research: Serves as a crucial building block for constructing complex molecular architectures in drug discovery programs.
• Kinase Inhibitor Synthesis: Used in the preparation of potential kinase inhibitors for targeted cancer therapies.
• CNS Drug Development: Employed in the synthesis of compounds targeting neurological disorders.
• Agrochemical Intermediate: Potential application in the synthesis of new-generation crop protection agents.
• Material Science Research: May be investigated as a monomer or ligand precursor for advanced functional materials.

Basic Information

Product Name	6-Cyclobutylpicolinonitrile
CAS No.	1240604-75-4
Molecular Formula	C10H10N2
Molecular Weight	158.20 g/mol
Synonyms	6-Cyclobutylpyridine-2-carbonitrile; 2-Cyano-6-cyclobutylpyridine; Picolinonitrile, 6-cyclobutyl-; 6-Cyclobutyl-2-cyanopyridine; 2-Pyridinecarbonitrile, 6-cyclobutyl-
EINECS	Contact for details

Quality Control

Our 6-Cyclobutylpicolinonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.