Description

Ethyl 4-Amino-5-Bromonicotinate is a high-purity, versatile nicotinate derivative and a key brominated pyridine building block. This compound is essential for advanced organic synthesis, offering a reactive handle for further functionalization in complex molecule construction. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Serves as a building block for developing new pesticides and herbicides with enhanced efficacy.
• Chemical Synthesis: Used in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the bromonicotinate moiety into larger molecular frameworks.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for metal catalysis and organocatalysts.
• Material Science Precursor: Potential use in synthesizing functionalized organic materials and electronic chemicals.
• Academic & R&D: A valuable reagent for methodological studies and exploring new synthetic routes in university and industrial laboratories.

Basic Information

Item	Detail
Product Name	Ethyl 4-Amino-5-Bromonicotinate
CAS No.	1240595-43-0
Molecular Formula	C8H9BrN2O2
Molecular Weight	245.08 g/mol
Synonyms	4-Amino-5-bromonicotinic acid ethyl ester; 5-Bromo-4-aminonicotinic acid ethyl ester; Ethyl 5-bromo-4-aminonicotinate; 4-Amino-5-bromo-3-pyridinecarboxylic acid ethyl ester; 3-Pyridinecarboxylic acid, 4-amino-5-bromo-, ethyl ester; Ethyl 4-amino-5-bromo-3-pyridinecarboxylate; 1240595-43-0
EINECS	Contact for details

Quality Control

Our Ethyl 4-Amino-5-Bromonicotinate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with your specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.