Description

n-((S)-1-Amino-3-(4-(8-((S)-1-Hydroxyethyl)Imidazo[1,2-A]Pyridin-2-Yl)Phenyl)Propan-2-Yl)-3-Chloro-4-Isopropoxybenzamide is a high-purity, chiral organic compound designed for advanced pharmaceutical research and development. This molecule serves as a critical building block or intermediate in the synthesis of novel therapeutic agents, particularly in targeted drug discovery programs. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require precise, high-quality chemical entities to drive innovation in medicinal chemistry.

Application

This specialized chemical intermediate is primarily utilized in sophisticated research and development settings. Key application areas include:

• Pharmaceutical Intermediate: Serving as a key chiral synthon in the multi-step synthesis of potential active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or probes for biological target identification and validation.
• Process Chemistry & Scale-Up: Evaluation and development of synthetic routes for the efficient, large-scale production of complex molecules.
• Academic & Institutional Research: Supporting fundamental research in organic synthesis and chemical biology at universities and research institutes.

Basic Information

Product Name	n-((S)-1-Amino-3-(4-(8-((S)-1-Hydroxyethyl)Imidazo[1,2-A]Pyridin-2-Yl)Phenyl)Propan-2-Yl)-3-Chloro-4-Isopropoxybenzamide
CAS No.	1240137-87-4
Molecular Formula	C28H31ClN4O3
Molecular Weight	507.03 g/mol
Synonyms	3-Chloro-4-isopropoxy-N-[(2S)-1-[[(1S)-1-(8-imidazo[1,2-a]pyridinyl)ethyl]amino]-3-[4-(8-imidazo[1,2-a]pyridinyl)phenyl]-2-propanyl]benzamide; UNII-1K8F5K216Y; 1K8F5K216Y; Benzamide, 3-chloro-4-(1-methylethoxy)-N-[(1S)-1-[[(1S)-1-(8-imidazo[1,2-a]pyridinyl)ethyl]amino]-3-[4-(8-imidazo[1,2-a]pyridinyl)phenyl]-2-propanyl]-; (S)-N-(1-Amino-3-(4-(8-((S)-1-hydroxyethyl)imidazo[1,2-a]pyridin-2-yl)phenyl)propan-2-yl)-3-chloro-4-isopropoxybenzamide
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing results from techniques such as HPLC, NMR, and chiral analysis. We support development under cGMP guidelines where required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when necessary to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.