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3-Chloro-n-((S)-1-(1,3-Dioxoisoindolin-2-Yl)-3-(4-(8-((S)-1-Hydroxyethyl)Imidazo[1,2-A]Pyridin-2-Yl)Phenyl)Propan-2-Yl)-4-Isopropoxybenzamide CAS NO 1240137-67-0
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CAS No.:1240137-67-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3-Chloro-n-((S)-1-(1,3-Dioxoisoindolin-2-Yl)-3-(4-(8-((S)-1-Hydroxyethyl)Imidazo[1,2-A]Pyridin-2-Yl)Phenyl)Propan-2-Yl)-4-Isopropoxybenzamide is a high-purity, complex organic intermediate with a defined stereochemistry. This compound is critical for pharmaceutical research and development, particularly in the synthesis of targeted therapeutic agents. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical and biotechnology sectors working on novel drug candidates.
Application
- Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical development.
- Biochemical Research: Used as a reference standard or a precursor in proteomics and enzyme inhibition studies.
- Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
- Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
- Academic Research: Utilized in university and institutional labs for investigating new synthetic pathways and biological mechanisms.
Basic Information
| Product Name | 3-Chloro-n-((S)-1-(1,3-Dioxoisoindolin-2-Yl)-3-(4-(8-((S)-1-Hydroxyethyl)Imidazo[1,2-A]Pyridin-2-Yl)Phenyl)Propan-2-Yl)-4-Isopropoxybenzamide |
| CAS No. | 1240137-67-0 |
| Molecular Formula | C35H31ClN4O5 |
| Molecular Weight | 623.10 g/mol |
| Synonyms | 3-Chloro-N-[(2S)-1-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-3-[4-[8-[(1S)-1-hydroxyethyl]imidazo[1,2-a]pyridin-2-yl]phenyl]propan-2-yl]-4-(propan-2-yloxy)benzamide; 1240137-67-0; UNII-2Q8H1Q6K4F; 2Q8H1Q6K4F; Benzamide, 3-chloro-N-[(2S)-1-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-3-[4-[8-[(1S)-1-hydroxyethyl]imidazo[1,2-a]pyridin-2-yl]phenyl]-2-propanyl]-4-(1-methylethoxy)-; (S)-3-Chloro-N-(1-(1,3-dioxoisoindolin-2-yl)-3-(4-(8-((S)-1-hydroxyethyl)imidazo[1,2-a]pyridin-2-yl)phenyl)propan-2-yl)-4-isopropoxybenzamide |
| EINECS | Contact for details |
Quality Control
Our 3-Chloro-n-((S)-1-(1,3-Dioxoisoindolin-2-Yl)-3-(4-(8-((S)-1-Hydroxyethyl)Imidazo[1,2-A]Pyridin-2-Yl)Phenyl)Propan-2-Yl)-4-Isopropoxybenzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure identity, potency, and purity meet exacting standards. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (HPLC) | Conforms to reference standard |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Chiral Purity (Chiral HPLC) | ≥ 99.0% ee |
| Water Content (KF) | ≤ 0.5% |
| Residual Solvents (GC) | Complies with ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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