Description

Ethyl 3-(3-Fluorophenyl)-1,2,4-Oxadiazole-5-Carboxylate is a high-value fluorinated heterocyclic building block, specifically a 1,2,4-oxadiazole derivative. This compound is of significant interest for its role as a key synthetic intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and advanced material sectors seeking to incorporate the 3-fluorophenyl-1,2,4-oxadiazole pharmacophore into new molecular entities.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of drug candidates targeting a wide range of therapeutic areas, including central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Research: Serves as a key precursor in the development of new-generation herbicides, fungicides, and insecticides, where the fluorinated oxadiazole core can enhance biological activity and stability.
• Chemical Biology & Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and high-throughput screening libraries to explore novel bioactive compounds.
• Material Science Precursor: Potential intermediate for synthesizing specialty polymers or organic electronic materials with tailored properties.
• Contract Research & Development (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client projects.

Basic Information

Product Name	Ethyl 3-(3-Fluorophenyl)-1,2,4-Oxadiazole-5-Carboxylate
CAS No.	1239736-58-3
Molecular Formula	C11H9FN2O3
Molecular Weight	236.20 g/mol
Synonyms	5-Ethoxycarbonyl-3-(3-fluorophenyl)-1,2,4-oxadiazole; Ethyl 5-(3-fluorophenyl)-1,2,4-oxadiazole-3-carboxylate; 3-(3-Fluorophenyl)-1,2,4-oxadiazole-5-carboxylic acid ethyl ester; 1,2,4-Oxadiazole-5-carboxylic acid, 3-(3-fluorophenyl)-, ethyl ester; 3-(3-Fluorophenyl)-5-(ethoxycarbonyl)-1,2,4-oxadiazole; 5-Carbethoxy-3-(3-fluorophenyl)-1,2,4-oxadiazole
EINECS	Contact for details

Quality Control

Our Ethyl 3-(3-Fluorophenyl)-1,2,4-Oxadiazole-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.