Description

2-[4-(Aminomethyl)Piperidin-1-Yl]Nicotinonitrile is a high-purity, advanced pharmaceutical intermediate featuring a unique piperidine-nicotinonitrile scaffold. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel bioactive molecules, particularly in medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting specific enzymes and receptors.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Kinase Inhibitor Development: Used in the research and development of potent and selective kinase inhibitors for oncology and inflammatory diseases.
• Chemical Biology Probes: Employed in the design of molecular probes to study biological pathways and protein functions.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	2-[4-(Aminomethyl)Piperidin-1-Yl]Nicotinonitrile
CAS No.	1239727-91-3
Molecular Formula	C12H16N4
Molecular Weight	216.28 g/mol
Synonyms	2-(4-(Aminomethyl)piperidin-1-yl)nicotinonitrile; 2-[4-(Aminomethyl)-1-piperidinyl]-3-pyridinecarbonitrile; Nicotinonitrile, 2-[4-(aminomethyl)-1-piperidinyl]-; 1-(3-Cyanopyridin-2-yl)-4-(aminomethyl)piperidine; 2-(4-(Aminomethyl)piperidin-1-yl)pyridine-3-carbonitrile; 1239727-91-3; 2-(4-(Aminomethyl)piperidino)nicotinonitrile
EINECS	Contact for details

Quality Control

Our 2-[4-(Aminomethyl)Piperidin-1-Yl]Nicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications in GMP and non-GMP pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.