Description

Carbamic Acid, n-(6-Aminospiro[3.3]Hept-2-Yl)-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic structure. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for creating new therapeutic candidates targeting central nervous system (CNS) and other complex diseases.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of novel drug candidates, particularly those with spirocyclic architectures.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry Development: Serves as a key starting material or intermediate for scaling up API synthesis under Good Manufacturing Practice (GMP) conditions.
• CNS Drug Discovery: Its structural features make it valuable for researching potential treatments for neurological and psychiatric disorders.
• Proteolysis Targeting Chimera (PROTAC) Development: Can be utilized in the synthesis of linker components for bifunctional degrader molecules.
• Chemical Biology Probes: Acts as a precursor for creating specialized molecular tools to study biological pathways and protein function.

Basic Information

Product Name	Carbamic Acid, n-(6-Aminospiro[3.3]Hept-2-Yl)-, 1,1-Dimethylethyl Ester
CAS No.	1239589-52-6
Molecular Formula	C14H24N2O2
Molecular Weight	252.35 g/mol
Synonyms	tert-Butyl N-(6-aminospiro[3.3]heptan-2-yl)carbamate; (6-Aminospiro[3.3]hept-2-yl)carbamic acid tert-butyl ester; 2-((tert-Butoxycarbonyl)amino)-6-aminospiro[3.3]heptane; N-Boc-2,6-diaminospiro[3.3]heptane; Boc-6-Amino-spiro[3.3]heptane-2-amine; 1239589-52-6; Spiro[3.3]heptane-2,6-diamine, N2-BOC-; tert-Butyl (6-aminospiro[3.3]hept-2-yl)carbamate
EINECS	Contact for details

Quality Control

Our Carbamic Acid, n-(6-Aminospiro[3.3]Hept-2-Yl)-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring the material is suitable for advanced research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment to prevent degradation. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.