Description

5-Iodo-2-(Trifluoromethyl)Pyridin-4-Amine CAS NO 1239462-10-2 is a high-value, halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both iodine and trifluoromethyl substituents, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science: Building block for creating specialty polymers, liquid crystals, and organic electronic materials that require specific halogenated motifs.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form complex biaryl structures.
• Chemical Biology & Proteomics: Utilized as a molecular tag or probe in bioconjugation and labeling studies due to its reactive amine and halogen functional groups.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated pyridine scaffolds.

Basic Information

Product Name	5-Iodo-2-(Trifluoromethyl)Pyridin-4-Amine
CAS No.	1239462-10-2
Molecular Formula	C6H4F3IN2
Molecular Weight	288.01 g/mol
Synonyms	4-Amino-5-iodo-2-(trifluoromethyl)pyridine; 2-(Trifluoromethyl)-5-iodopyridin-4-amine; 5-Iodo-2-trifluoromethyl-4-aminopyridine; 4-Pyridinamine, 5-iodo-2-(trifluoromethyl)-; 5-Iodo-4-amino-2-(trifluoromethyl)pyridine; 1239462-10-2; 5-I-2-CF3-4-NH2-Py
EINECS	Contact for details

Quality Control

Every batch of 5-Iodo-2-(Trifluoromethyl)Pyridin-4-Amine undergoes rigorous analytical testing to ensure it meets the high-purity standards required for research and development applications. Our quality assurance protocols are designed to guarantee batch-to-batch consistency and reliability. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and impurity profiles as determined by HPLC, NMR, and MS, is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in its original packaging to protect this light-sensitive and moisture-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.