Description

tert-Butyl 6-Chloro-2-Methylpyridin-3-Ylcarbamate is a high-purity, protected amine derivative used as a critical synthetic intermediate in advanced organic synthesis. Its primary value lies in providing a versatile and stable building block for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on new active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides, herbicides, and fungicides where the pyridine core is a common pharmacophore.
• Chemical Biology & Proteomics: Serves as a precursor for designing molecular probes, enzyme inhibitors, and other tools for biological research.
• Material Science Research: Employed in the development of novel organic electronic materials, ligands for catalysis, and specialty polymers.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	tert-Butyl 6-Chloro-2-Methylpyridin-3-Ylcarbamate
CAS No.	1238324-80-5
Molecular Formula	C11H15ClN2O2
Molecular Weight	242.70 g/mol
Synonyms	tert-Butyl (6-chloro-2-methylpyridin-3-yl)carbamate; 3-((tert-Butoxycarbonyl)amino)-6-chloro-2-methylpyridine; 6-Chloro-2-methylpyridin-3-amine, N-Boc-protected; Boc-6-Chloro-2-methyl-3-aminopyridine; N-Boc-3-Amino-6-chloro-2-methylpyridine; tert-Butyl N-(6-chloro-2-methyl-3-pyridinyl)carbamate; 1238324-80-5
EINECS	Contact for details

Quality Control

Our tert-Butyl 6-Chloro-2-Methylpyridin-3-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance in GMP and ISO environments for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.