Description

tert-Butyl 3-(4-Methylpyridin-2-Yl)Azetidine-1-Carboxylate is a high-value, nitrogen-containing heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the design and production of novel pesticides and herbicides, leveraging its azetidine and pyridine motifs.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-donor ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and protein function.
• Material Science Research: Acts as a building block for advanced polymers and functional organic materials with specific electronic or binding properties.

Basic Information

Product Name	tert-Butyl 3-(4-Methylpyridin-2-Yl)Azetidine-1-Carboxylate
CAS No.	1236861-42-9
Molecular Formula	C14H20N2O2
Molecular Weight	248.32 g/mol
Synonyms	1-Boc-3-(4-methylpyridin-2-yl)azetidine; 1-(tert-Butoxycarbonyl)-3-(4-methyl-2-pyridinyl)azetidine; tert-Butyl 3-(4-methyl-2-pyridinyl)azetidine-1-carboxylate; 3-(4-Methylpyridin-2-yl)azetidine-1-carboxylic acid tert-butyl ester; Azetidine-1-carboxylic acid, 3-(4-methyl-2-pyridinyl)-, 1,1-dimethylethyl ester; 2-(1-Boc-azetidin-3-yl)-4-methylpyridine; Boc-3-(4-methyl-2-pyridyl)azetidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(4-Methylpyridin-2-Yl)Azetidine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.