Description

1-(4-Bromo-Phenyl)-Cyclopentanecarboxylic Acid Methyl Ester is a high-purity, versatile brominated aromatic ester building block essential for advanced organic synthesis. Its core value lies in providing a functionalized cyclopentane ring system with a bromine handle for further cross-coupling reactions and a methyl ester for hydrolysis or transesterification. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Research: Serves as a precursor in the synthesis of new-generation herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Used to create specialized phosphine or nitrogen-based ligands for asymmetric catalysis and transition metal complexes.
• Material Science Monomer: Potential building block for specialty polymers and liquid crystals, leveraging the rigid cyclopentane and aromatic structure.
• Chemical Biology Probe Synthesis: Employed in the design and synthesis of molecular probes for target identification and validation in biological systems.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	1-(4-Bromo-Phenyl)-Cyclopentanecarboxylic Acid Methyl Ester
CAS No.	1236357-64-4
Molecular Formula	C13H15BrO2
Molecular Weight	283.16 g/mol
Synonyms	Methyl 1-(4-bromophenyl)cyclopentanecarboxylate; 1-(4-Bromophenyl)cyclopentanecarboxylic acid methyl ester; 4-Bromo-alpha,α-cyclopentanedibenzeneacetic acid methyl ester; Cyclopentanecarboxylic acid, 1-(4-bromophenyl)-, methyl ester; Methyl 1-(p-bromophenyl)cyclopentanecarboxylate; 1-(p-Bromophenyl)cyclopentanecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of 1-(4-Bromo-Phenyl)-Cyclopentanecarboxylic Acid Methyl Ester is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with detailed control of related substances. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for identity, assay, and impurity profiles. We support development and commercial projects with custom synthesis and scale-up capabilities to meet specific purity or packaging requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.