Description

Methyl 2-Iodo-4-(Trifluoromethyl)Benzoate is a high-value, multi-functional aromatic ester building block designed for advanced synthetic chemistry. Its molecular architecture, featuring both an iodine substituent and a trifluoromethyl group, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as cross-coupling reactions and the synthesis of fluorinated active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves biological activity and environmental persistence.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials due to its unique halogenated and fluorinated structure.
• Cross-Coupling Reactions: The iodine atom acts as an excellent handle for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings, enabling rapid diversification of molecular scaffolds.
• Fluorine Chemistry: An essential reagent for introducing the -CF3 moiety into target molecules, a common strategy in modern medicinal and agrochemistry.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds and molecular probes for studying biological mechanisms and target engagement.

Basic Information

Product Name	Methyl 2-Iodo-4-(Trifluoromethyl)Benzoate
CAS No.	1236303-09-5
Molecular Formula	C9H6F3IO2
Molecular Weight	330.04 g/mol
Synonyms	Methyl 2-Iodo-α,α,α-trifluoro-p-toluate; 2-Iodo-4-(trifluoromethyl)benzoic Acid Methyl Ester; Benzoic acid, 2-iodo-4-(trifluoromethyl)-, methyl ester; Methyl 2-iodo-α,α,α-trifluoro-p-toluate; Methyl 2-iodo-4-trifluoromethylbenzoate; Methyl 2-iodo-4-(trifluoromethyl)benzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Iodo-4-(Trifluoromethyl)Benzoate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and undergoes rigorous analytical testing. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.