Description

Ethyl 3-(3-Fluoro-4-Hydroxyphenyl)-2-Methylpropanoate is a high-purity fluorinated aromatic ester building block designed for advanced organic synthesis. This compound is valued for its unique molecular architecture, which incorporates both a phenolic hydroxyl group and a fluorine atom on the phenyl ring, making it a versatile intermediate for creating novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and process chemistry applications.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic components in electronic display materials, improving charge transport and thermal properties.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce fluorinated phenolic groups into specialty polymer backbones.
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new synthetic methodologies involving fluorophenols.

Basic Information

Product Name	Ethyl 3-(3-Fluoro-4-Hydroxyphenyl)-2-Methylpropanoate
CAS No.	1234848-20-4
Molecular Formula	C₁₂H₁₅FO₃
Molecular Weight	226.24 g/mol
Synonyms	Ethyl 3-(3-Fluoro-4-hydroxyphenyl)-2-methylpropionate; 2-Methyl-3-(3-fluoro-4-hydroxyphenyl)propionic Acid Ethyl Ester; 3-(3-Fluoro-4-Hydroxyphenyl)-2-Methylpropanoic Acid Ethyl Ester; 3-Fluoro-4-hydroxy-α-methylhydrocinnamic Acid Ethyl Ester; Ethyl 3-(3-Fluoro-4-Hydroxybenzyl)butyrate; FHPMPE; CAS 1234848-20-4
EINECS	Contact for details

Quality Control

Our Ethyl 3-(3-Fluoro-4-Hydroxyphenyl)-2-Methylpropanoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the stringent requirements of research and process development. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.