Description

tert-Butyl 7-Oxo-2,6-diazaspiro[3.4]octane-2-carboxylate is a high-value, advanced pharmaceutical intermediate featuring a constrained spirocyclic scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules targeting challenging disease pathways. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of new therapeutic agents, including protease inhibitors and other enzyme-targeted drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing spirocyclic and diazepane motifs.
• Medicinal Chemistry & Drug Discovery: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Protease Inhibitor Development: Used in the research and synthesis of potential inhibitors for various proteases, a significant target class in oncology and virology.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs/CMOs) serving the pharmaceutical industry.

Basic Information

Product Name	tert-Butyl 7-Oxo-2,6-diazaspiro[3.4]octane-2-carboxylate
CAS No.	1234616-51-3
Molecular Formula	C11H18N2O3
Molecular Weight	226.27 g/mol
Synonyms	2,6-Diazaspiro[3.4]octane-2-carboxylic acid, 7-oxo-, 1,1-dimethylethyl ester; 7-Oxo-2,6-diazaspiro[3.4]octane-2-carboxylic acid tert-butyl ester; tert-Butyl 7-oxo-2,6-diazaspiro[3.4]octane-2-carboxylate; 2-tert-Butoxycarbonyl-2,6-diazaspiro[3.4]octan-7-one; Boc-2,6-diazaspiro[3.4]octan-7-one; 2-(tert-Butoxycarbonyl)-2,6-diazaspiro[3.4]octan-7-one
EINECS	Contact for details

Quality Control

Our tert-Butyl 7-Oxo-2,6-diazaspiro[3.4]octane-2-carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full batch traceability are provided and can be tailored to meet specific client requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.