Description

1H-Pyrazolo[3,4-B]Pyridine-1-Carboxylic Acid, 3-Bromo-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate and versatile chemical building block. Its value lies in its functionalized heterocyclic structure, which is critical for constructing complex molecules in medicinal chemistry and materials science. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop novel drug candidates.
• Agrochemical Synthesis: Serves as a precursor for developing new crop protection agents and pesticides.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and other transformations to introduce the pyrazolopyridine scaffold into target molecules.
• Material Science: Potential use in the development of organic electronic materials and ligands for catalysis.

Basic Information

Product Name	1H-Pyrazolo[3,4-B]Pyridine-1-Carboxylic Acid, 3-Bromo-, 1,1-Dimethylethyl Ester
CAS No.	1234616-46-6
Molecular Formula	C12H14BrN3O2
Molecular Weight	312.16 g/mol
Synonyms	3-Bromo-1H-pyrazolo[3,4-b]pyridine-1-carboxylic acid tert-butyl ester; tert-Butyl 3-bromo-1H-pyrazolo[3,4-b]pyridine-1-carboxylate; 3-Bromo-1-(tert-butoxycarbonyl)-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine-1-carboxylic acid, 3-bromo-, 1,1-dimethylethyl ester; 3-Bromo-1-Boc-1H-pyrazolo[3,4-b]pyridine; 3-Bromo-1H-pyrazolo[3,4-b]pyridine-1-carboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 1H-Pyrazolo[3,4-B]Pyridine-1-Carboxylic Acid, 3-Bromo-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP standards where applicable to support our clients in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere if long-term storage is required to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.