Description

6-Bromo-4-Azaindole-2-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a versatile and valuable building block for the synthesis of complex heterocyclic molecules, particularly those targeting kinase inhibition and other therapeutic pathways. It is primarily needed by research institutions, contract research organizations (CROs), and pharmaceutical companies engaged in the development of novel small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent kinase inhibitors and other biologically active compounds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to develop new drug candidates.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying enzyme function and cellular signaling pathways.
• Heterocyclic Compound Synthesis: Serves as a foundational scaffold for constructing complex fused-ring systems with potential pharmacological activity.
• Contract Manufacturing: Supplied to CDMOs for the scale-up and production of active pharmaceutical ingredients (APIs) under cGMP conditions.

Basic Information

Product Name	6-Bromo-4-Azaindole-2-Carboxylic Acid Ethyl Ester
CAS No.	1234616-09-1
Molecular Formula	C10H9BrN2O2
Molecular Weight	269.10 g/mol
Synonyms	Ethyl 6-Bromo-1H-pyrrolo[2,3-b]pyridine-2-carboxylate; 6-Bromo-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid ethyl ester; 6-Bromo-4-azaindole-2-ethyl carboxylate; 6-Bromo-7-azaindole-2-carboxylic acid ethyl ester; 6-Bromo-1H-7-azaindole-2-carboxylic acid ethyl ester; 6-Bromo-4-aza-1H-indole-2-carboxylic acid ethyl ester; 6-Bromo-4-azaindole-2-ethyl ester
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Azaindole-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.