Description

1H-Pyrazolo[4,3-B]Pyridine-3-Carboxylicacid,6-Bromo-,Ethylester is a high-purity, advanced pharmaceutical intermediate characterized by its distinct heterocyclic pyrazolopyridine scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors, particularly those focused on kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis Building Block: Employed in multi-step organic syntheses to introduce the functionalized pyrazolopyridine core into more complex molecules.
• Biochemical Research: May serve as a starting material or reference standard in biochemical assays and pharmacological studies.
• Process Chemistry Development: Used for scaling up synthetic routes and optimizing manufacturing processes for potential APIs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the life sciences industry.

Basic Information

Product Name	1H-Pyrazolo[4,3-B]Pyridine-3-Carboxylicacid,6-Bromo-,Ethylester
CAS No.	1234616-05-7
Molecular Formula	C10H8BrN3O2
Molecular Weight	282.10 g/mol
Synonyms	6-Bromo-1H-pyrazolo[4,3-b]pyridine-3-carboxylic acid ethyl ester; Ethyl 6-bromo-1H-pyrazolo[4,3-b]pyridine-3-carboxylate; 6-Bromo-1H-pyrazolo[4,3-b]pyridine-3-carboxylic acid ethyl ester; 1H-Pyrazolo[4,3-b]pyridine-3-carboxylic acid, 6-bromo-, ethyl ester; 6-Bromo-1H-pyrazolo[4,3-b]pyridine-3-carboxylic acid ethyl ester; Ethyl 6-bromo-1H-pyrazolo[4,3-b]pyridine-3-carboxylate; 1234616-05-7; 6-Bromo-1H-pyrazolo[4,3-b]pyridine-3-carboxylic acid, ethyl ester
EINECS	Contact for details

Quality Control

Our 1H-Pyrazolo[4,3-B]Pyridine-3-Carboxylicacid,6-Bromo-,Ethylester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and stringent in-process controls guarantees a reliable supply of this high-value intermediate for critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.