Description

1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid, 6-Chloro-, Methyl Ester is a high-purity, advanced pharmaceutical intermediate with a defined heterocyclic structure. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly for targeted therapies. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially kinase inhibitors and other targeted oncology treatments.
• Organic Synthesis Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization due to its versatile pyrrolopyridine scaffold.
• Research & Development (R&D): Essential for academic and industrial research labs focusing on heterocyclic chemistry and new therapeutic modalities.
• Agrochemical Research: Potential intermediate in the development of novel agrochemicals requiring specific nitrogen-containing heterocycles.
• Material Science Precursor: Can serve as a starting material for synthesizing specialized ligands or organic electronic materials.

Basic Information

Item	Details
Product Name	1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid, 6-Chloro-, Methyl Ester
CAS No.	1234615-81-6
Molecular Formula	C10H7ClN2O2
Molecular Weight	222.63 g/mol
Synonyms	6-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid methyl ester; Methyl 6-chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylate; 6-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid methyl ester; 6-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid, methyl ester; 6-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid methyl ester (CAS 1234615-81-6); 6-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid, methyl ester (CAS 1234615-81-6); Methyl 6-chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylate (CAS 1234615-81-6)
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid, 6-Chloro-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.