Description

(1R,4R)-4-(3-Nitropyridine-2-Ylamino)Cyclohexanol is a high-purity, stereochemically defined chiral intermediate of significant importance in advanced pharmaceutical synthesis. This compound matters because its specific stereochemistry and functional groups make it a critical building block for developing novel, targeted therapeutic agents. It is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and process development of new drugs, particularly in areas requiring complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the multi-step synthesis of potential active pharmaceutical ingredients (APIs).
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization campaigns.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for new drug candidates.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in catalytic asymmetric reactions to construct complex molecules.
• Chemical Biology Probes: Can be incorporated into molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	(1R,4R)-4-(3-Nitropyridine-2-Ylamino)Cyclohexanol
CAS No.	1233955-42-4
Molecular Formula	C11H15N3O3
Molecular Weight	237.26 g/mol
Synonyms	(1R,4R)-4-[(3-Nitro-2-pyridinyl)amino]cyclohexanol; (1R,4R)-4-((3-Nitropyridin-2-yl)amino)cyclohexan-1-ol; 2-[[(1R,4R)-4-Hydroxycyclohexyl]amino]-3-nitropyridine; (1R,4R)-4-(3-Nitro-pyridin-2-ylamino)-cyclohexanol; (1R,4R)-4-[(3-Nitro-2-pyridyl)amino]cyclohexanol; 4-[(3-Nitro-2-pyridinyl)amino]cyclohexanol, (1R,4R)-rel-; (1R,4R)-4-(3-Nitropyridin-2-ylamino)cyclohexanol
EINECS	Contact for details

Quality Control

Our (1R,4R)-4-(3-Nitropyridine-2-Ylamino)Cyclohexanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to cGMP guidelines for the production of pharmaceutical intermediates, ensuring traceability and documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and away from incompatible materials. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.