Description

(S)-1-(5-Nitropyridin-2-Yl)Pyrrolidin-3-Amine Hydrochloride is a high-purity chiral amine derivative, specifically designed for advanced pharmaceutical research and development. This compound serves as a critical chiral intermediate or building block for synthesizing novel active pharmaceutical ingredients (APIs) and other fine chemicals. It is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and biotechnology sectors who require enantiomerically pure intermediates for drug discovery and process optimization.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of potential therapeutic agents, including kinase inhibitors and other small molecule drugs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and route development for API manufacturing.
• Agrochemical Synthesis: Potential intermediate in the development of enantiomerically pure pesticides or herbicides.
• Ligand and Catalyst Preparation: Can be utilized to synthesize chiral ligands for asymmetric catalysis.
• Reference Standard: Used as an analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(S)-1-(5-Nitropyridin-2-Yl)Pyrrolidin-3-Amine Hydrochloride
CAS No.	1233860-34-8
Molecular Formula	C9H13ClN4O2
Molecular Weight	244.68 g/mol
Synonyms	(3S)-1-(5-Nitro-2-pyridinyl)-3-pyrrolidinamine hydrochloride; (S)-3-Amino-1-(5-nitropyridin-2-yl)pyrrolidine hydrochloride; 1-(5-Nitropyridin-2-yl)-L-prolinamine hydrochloride; (S)-1-(5-Nitro-2-pyridyl)pyrrolidin-3-amine HCl; Pyrrolidin-3-amine, 1-(5-nitropyridin-2-yl)-, (3S)-, hydrochloride; 1233860-34-8; (S)-1-(5-Nitro-pyridin-2-yl)-pyrrolidin-3-ylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-1-(5-Nitropyridin-2-Yl)Pyrrolidin-3-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), chiral purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.