Description

6-Chlorochroman-4-Carboxylate is a high-purity organic intermediate characterized by its chroman core structure substituted with a chlorine atom and a carboxylate ester group. This compound matters as a versatile and critical building block in advanced organic synthesis, enabling the construction of complex molecules with precise stereochemistry. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated chroman scaffold.
• Fine Chemical Production: Serves as a precursor for specialty chemicals, dyes, and functional materials requiring a chiral benzopyran moiety.
• Academic & Industrial Research: A valuable reagent for methodological studies in organic chemistry, including asymmetric synthesis and catalysis.
• Ligand and Catalyst Development: Potential building block for creating chiral ligands and organocatalysts used in enantioselective transformations.

Basic Information

Product Name	6-Chlorochroman-4-Carboxylate
CAS No.	1233698-02-6
Molecular Formula	C10H9ClO3
Molecular Weight	212.63 g/mol
Synonyms	6-Chloro-3,4-dihydro-2H-1-benzopyran-4-carboxylic acid ester; 6-Chloro-4-carbethoxychroman; 6-Chloro-4-ethoxycarbonylchroman; 6-Chlorochroman-4-carboxylic acid ethyl ester; Ethyl 6-chlorochroman-4-carboxylate; 6-Chloro-3,4-dihydro-2H-chromene-4-carboxylate; 4-Carbethoxy-6-chlorochroman
EINECS	Contact for details

Quality Control

Our 6-Chlorochroman-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.