Description

(E)-Methyl 3-(5-Methoxypyridin-3-Yl)Acrylate is a high-purity, versatile acrylate ester building block featuring a substituted pyridine core. This compound is valued for its role as a key synthetic intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing potential drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic research.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its pyridine-acrylate structure for bioactivity.
• Material Science Research: Serves as a monomer or precursor for functional polymers and advanced organic materials with specific electronic or photonic properties.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Cross-Coupling Reactions: Acts as a substrate in various metal-catalyzed cross-coupling reactions (e.g., Heck, Suzuki) to create complex conjugated systems.
• Ligand and Catalyst Development: Used to prepare novel chelating ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	(E)-Methyl 3-(5-Methoxypyridin-3-Yl)Acrylate
CAS No.	1233560-96-7
Molecular Formula	C10H11NO3
Molecular Weight	193.20 g/mol
Synonyms	Methyl (2E)-3-(5-Methoxy-3-pyridinyl)-2-propenoate; (E)-Methyl 3-(5-Methoxypyridin-3-yl)acrylate; 3-Pyridineacrylic acid, 5-methoxy-, methyl ester, (E)-; Methyl (E)-3-(5-methoxypyridin-3-yl)acrylate; 5-Methoxy-3-pyridylacrylic acid methyl ester; (E)-3-(5-Methoxypyridin-3-yl)acrylic acid methyl ester
EINECS	Contact for details

Quality Control

Our (E)-Methyl 3-(5-Methoxypyridin-3-Yl)Acrylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.