Description

(S)-1,2,3,4-Tetrahydro-Pyridine-2-Carboxylic Acid CAS NO 1233501-63-7 is a high-value, non-proteinogenic amino acid derivative featuring a chiral center and a constrained piperidine-like ring structure. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the creation of complex molecules with precise stereochemistry. It is primarily utilized by pharmaceutical research organizations and fine chemical manufacturers developing novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of drug candidates targeting neurological disorders, metabolic diseases, and other therapeutic areas.
• Agrochemical Research: Used in the development of novel pesticides and herbicides where its unique scaffold can contribute to biological activity.
• Peptidomimetics & Constrained Peptides: Incorporated into peptide analogs to enhance metabolic stability, bioavailability, and receptor selectivity.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic & R&D Laboratories: Employed in methodological studies and the discovery of new chemical entities in medicinal chemistry.
• Fine Chemical Synthesis: A versatile intermediate for producing specialty chemicals, flavors, and fragrances requiring specific stereochemistry.

Basic Information

Product Name	(S)-1,2,3,4-Tetrahydro-Pyridine-2-Carboxylic Acid
CAS No.	1233501-63-7
Molecular Formula	C6H9NO2
Molecular Weight	127.14 g/mol
Synonyms	(S)-1,2,3,4-Tetrahydropyridine-2-carboxylic acid; (2S)-1,2,3,4-Tetrahydropyridine-2-carboxylic acid; L-1,2,3,4-Tetrahydropyridine-2-carboxylic acid; (S)-THPCA; (S)-2-Carboxy-1,2,3,4-tetrahydropyridine; (S)-Pipecolinic acid derivative; (S)-2-Piperidinecarboxylic acid, 1,2,3,4-tetrahydro-
EINECS	Contact for details

Quality Control

Our (S)-1,2,3,4-Tetrahydro-Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and chiral excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.