Description

(R)-Ethyl 2-(Piperidin-3-Yl)Acetic Acid Hydrochloride is a high-purity chiral building block and intermediate of significant importance in advanced organic synthesis. Its value lies in its defined stereochemistry and functional groups, which are critical for constructing complex molecules with specific biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, especially for central nervous system (CNS) targets.
• Asymmetric Synthesis: Used as a starting material or intermediate in catalytic asymmetric reactions to introduce the (R)-piperidinyl acetic acid moiety.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for creating libraries of bioactive compounds.
• Peptidomimetics Development: Serves as a constrained amino acid analog for designing and synthesizing peptide-like molecules with enhanced stability and potency.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme function and receptor interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production of clinical trial materials.

Basic Information

Product Name	(R)-Ethyl 2-(Piperidin-3-Yl)Acetic Acid Hydrochloride
CAS No.	1233200-48-0
Molecular Formula	C9H18ClNO2
Molecular Weight	207.70 g/mol
Synonyms	(R)-Ethyl 2-(3-Piperidyl)acetate hydrochloride; (R)-2-(Piperidin-3-yl)acetic acid ethyl ester hydrochloride; Ethyl (R)-2-(piperidin-3-yl)acetate HCl; (3R)-2-Piperidineacetic acid, ethyl ester, hydrochloride; (R)-Ethyl piperidin-3-ylacetate hydrochloride; (R)-3-Piperidineacetic acid ethyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-Ethyl 2-(Piperidin-3-Yl)Acetic Acid Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles. We adhere to relevant quality management standards to support our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.