Description

Propanedioic Acid, 2-Amino-, 1,3-Bis(1,1-Dimethylethyl) Ester is a specialized, high-purity chemical intermediate featuring a sterically hindered, amino-substituted malonate ester structure. This compound matters for its role as a critical building block in advanced organic synthesis, offering a protected amino acid derivative that enables precise molecular construction. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex active ingredients and novel materials.

Application

• As a key pharmaceutical intermediate in the synthesis of peptide mimetics and active pharmaceutical ingredients (APIs).
• Utilized in agrochemical research for constructing novel herbicide and pesticide molecules.
• Serves as a protected synthon in peptide coupling and solid-phase synthesis methodologies.
• Acts as a precursor for specialty polymers and functional materials requiring amino-acid-based monomers.
• Employed in asymmetric catalysis and chiral ligand development due to its stereogenic center.
• Used in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	Propanedioic Acid, 2-Amino-, 1,3-Bis(1,1-Dimethylethyl) Ester
CAS No.	1233077-82-1
Molecular Formula	C13H25NO4
Molecular Weight	259.34 g/mol
Synonyms	2-Aminomalonic Acid Di-tert-butyl Ester; Di-tert-butyl 2-Aminomalonate; 2-Amino-di-tert-butyl Malonate; tert-Butyl 2-Aminomalonate; Aminomalonic Acid Di-tert-butyl Ester; 1,3-Bis(1,1-dimethylethyl) 2-Aminopropanedioate; DBU Aminomalonate; (Aminomethylene)dimethylmalonic Acid Di-tert-butyl Ester
EINECS	Contact for details

Quality Control

Our production of Propanedioic Acid, 2-Amino-, 1,3-Bis(1,1-Dimethylethyl) Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We support cGMP-compliant manufacturing for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.