Description

8-Bromo-3-Iodo-Imidazo[1,2-A]Pyridine is a high-purity, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, enabling complex molecular architectures through selective cross-coupling reactions. It is primarily needed by research institutions and industrial R&D departments focused on medicinal chemistry, particularly in the discovery of new active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, especially for kinase inhibitors and other biologically active small molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi couplings due to the presence of both bromo and iodo substituents, allowing for sequential functionalization.
• Medicinal Chemistry Library Synthesis: Employed in the construction of diverse compound libraries for high-throughput screening against various biological targets.
• Chemical Biology Probes: Used to develop molecular probes for studying enzyme function and cellular pathways.

Basic Information

Product Name	8-Bromo-3-Iodo-Imidazo[1,2-A]Pyridine
CAS No.	1232038-69-5
Molecular Formula	C7H4BrIN2
Molecular Weight	322.93 g/mol
Synonyms	Imidazo[1,2-a]pyridine, 8-bromo-3-iodo-; 3-Iodo-8-bromoimidazo[1,2-a]pyridine; 8-Bromo-3-iodoimidazo[1,2-a]pyridine; 8-Bromo-3-iodoimidazo[1,2-a]pyridine; 1232038-69-5; AI3-63590; ZINC000103249544; BRN 12513352
EINECS	Contact for details

Quality Control

Our 8-Bromo-3-Iodo-Imidazo[1,2-A]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards expected for pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.