Description

Methyl 5-(2,6-Difluorophenyl)Pyridine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its difluorophenyl and pyridine carboxylate structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. It is primarily sought after by R&D laboratories and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially in kinase inhibitor and anti-inflammatory agent research.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging the biological activity of the difluorophenyl moiety.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis and material science applications.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke organic synthesis.
• Academic Research: Employed in university and institutional labs for methodological development and novel heterocyclic chemistry studies.

Basic Information

Product Name	Methyl 5-(2,6-Difluorophenyl)Pyridine-3-Carboxylate
CAS No.	1229626-86-1
Molecular Formula	C13H9F2NO2
Molecular Weight	249.21 g/mol
Synonyms	Methyl 5-(2,6-difluorophenyl)nicotinate; 3-Pyridinecarboxylic acid, 5-(2,6-difluorophenyl)-, methyl ester; 5-(2,6-Difluorophenyl)nicotinic acid methyl ester; Methyl 5-(2,6-difluorophenyl)-3-pyridinecarboxylate; 1229626-86-1; Methyl 5-(2,6-difluorophenyl)pyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 5-(2,6-Difluorophenyl)Pyridine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for advanced synthetic intermediates. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.