Description

Carbamic Acid, n-[2-[2-(2-Oxoethoxy)Ethoxy]Ethyl]-, 1,1-Dimethylethyl Ester is a specialized organic compound featuring a carbamate core protected by a tert-butyl group and linked to a polyethylene glycol-like chain terminated with an aldehyde. This unique bifunctional structure makes it a valuable intermediate for the synthesis of complex molecules, particularly in advanced pharmaceutical and bioconjugation applications. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require high-purity, functionalized building blocks for drug discovery and development.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring PEGylation or specific linker chemistry.
• Bioconjugation Reagent: The aldehyde-terminated PEG chain enables site-specific conjugation to proteins, antibodies, or peptides for creating antibody-drug conjugates (ADCs) or diagnostic probes.
• Polymer Chemistry: Acts as a functional monomer or cross-linking agent for synthesizing specialized polymers with tailored properties for drug delivery systems.
• Protecting Group Strategy: The tert-butyl carbamate (Boc) group is widely used for the temporary protection of amines in multi-step organic synthesis.
• Linker for Solid-Phase Synthesis: Useful in peptide and oligonucleotide synthesis where a cleavable linker with specific spacing and functionality is required.
• Material Science Research: Employed in the development of novel functional materials, surfaces, and coatings that require specific chemical handles.

Basic Information

Product Name	Carbamic Acid, n-[2-[2-(2-Oxoethoxy)Ethoxy]Ethyl]-, 1,1-Dimethylethyl Ester
CAS No.	1229024-41-2
Molecular Formula	C13H25NO6
Molecular Weight	291.34 g/mol
Synonyms	tert-Butyl (2-(2-(2-oxoethoxy)ethoxy)ethyl)carbamate; Boc-NH-PEG2-CHO; 2-[2-(Boc-amino)ethoxy]ethoxyacetaldehyde; N-Boc-2,2'-(ethylenedioxy)diethylamine aldehyde; N-(tert-Butoxycarbonyl)-2,2'-(ethylenedioxy)bis(ethylamine) aldehyde; Aldehyde-PEG2-Boc-amine; Boc-amine-PEG2-CHO
EINECS	Contact for details

Quality Control

Our Carbamic Acid, n-[2-[2-(2-Oxoethoxy)Ethoxy]Ethyl]-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is moisture-sensitive and should be handled under anhydrous conditions when possible. Allow the container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.