Description

(E)-Benzyl 4-Bromostyrylcarbamate CAS NO 1228957-12-7 is a high-purity, advanced pharmaceutical intermediate characterized by its distinct brominated styryl carbamate structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromine and carbamate functionalities into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in oncology and CNS therapeutic areas.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and lead optimization due to its modifiable bromine and carbamate groups.
• Agrochemical Synthesis: Serves as a precursor in the development of novel pesticides and herbicides.
• Chemical Biology Probe Development: Employed in the synthesis of molecular probes for studying biological pathways and target engagement.
• Polymer & Material Science: Can be incorporated as a functional monomer or cross-linking agent in specialty polymer formulations.
• Academic & Institutional Research: Used in university and contract research organization (CRO) laboratories for exploratory synthetic chemistry.

Basic Information

Item	Details
Product Name	(E)-Benzyl 4-Bromostyrylcarbamate
CAS No.	1228957-12-7
Molecular Formula	C16H14BrNO2
Molecular Weight	332.19 g/mol
Synonyms	Benzyl (E)-3-(4-bromophenyl)acrylate carbamate; (E)-Benzyl (3-(4-bromophenyl)acryloyl)carbamate; 4-Bromostyrylcarbamic Acid Benzyl Ester; (E)-Benzyl N-(3-(4-bromophenyl)acryloyl)carbamate; Benzyl (E)-4-Bromocinnamylcarbamate; Bn-4-Br-Styryl-Carbamate
EINECS	Contact for details

Quality Control

Our (E)-Benzyl 4-Bromostyrylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.