Description

5-Chloro-3-Isopropoxy-2-Methoxypyridine is a high-purity, synthetically valuable pyridine derivative. This compound serves as a critical advanced pharmaceutical intermediate and versatile organic building block for complex molecule synthesis. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries to construct novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, leveraging its halogenated and alkoxy-substituted pyridine core.
• Ligand and Catalyst Development: Used in organometallic chemistry to create specialized ligands for catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Intermediate for synthesizing functionalized polymers, liquid crystals, and electronic materials requiring specific pyridine-based architectures.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes and tool compounds used in biochemical and pharmacological research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	5-Chloro-3-Isopropoxy-2-Methoxypyridine
CAS No.	1228957-00-3
Molecular Formula	C9H12ClNO2
Molecular Weight	201.65 g/mol
Synonyms	2-Methoxy-5-chloro-3-isopropoxypyridine; 5-Chloro-2-methoxy-3-(propan-2-yloxy)pyridine; 3-Isopropoxy-5-chloro-2-methoxypyridine; 5-Chloro-3-(1-methylethoxy)-2-methoxypyridine; Pyridine, 5-chloro-3-(1-methylethoxy)-2-methoxy-; 1228957-00-3
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-Isopropoxy-2-Methoxypyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and high-reliability research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.