Description

5-Amino-1-Methylpiperidin-2-One Hydrochloride is a high-purity organic salt compound, serving as a critical building block in advanced pharmaceutical synthesis. Its value lies in providing a functionalized piperidinone scaffold essential for constructing complex molecules with targeted biological activity. This intermediate is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly within medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, especially in central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing and screening compound libraries in drug discovery.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the multi-step synthesis of complex target molecules during process development and scale-up.
• Chemical Biology Probes: Serves as a precursor for labeled compounds or probes used in biochemical and pharmacological studies.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and contract research organizations (CROs/CMOs).

Basic Information

Product Name	5-Amino-1-Methylpiperidin-2-One Hydrochloride
CAS No.	1228838-10-5
Molecular Formula	C6H13N2O·HCl
Molecular Weight	164.64 g/mol (Free base: 128.18 g/mol)
Synonyms	1-Methyl-5-aminopiperidin-2-one hydrochloride; 5-Amino-1-methyl-2-piperidinone hydrochloride; 2-Piperidinone, 5-amino-1-methyl-, hydrochloride; 5-Amino-1-methylpiperidin-2-one HCl; 1-Methyl-5-aminopiperidin-2-one HCl; 5-Amino-1-methyl-2-piperidinone HCl
EINECS	Contact for details

Quality Control

Our 5-Amino-1-Methylpiperidin-2-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay, impurity profile, and residual solvents are provided and available upon request, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.