Description

2-(2-(Hydroxymethyl)Piperidin-1-Yl)Acetic Acid is a versatile piperidine derivative carboxylic acid, serving as a critical building block in advanced organic synthesis. Its bifunctional structure, featuring both a hydroxymethyl and a carboxylic acid group on the piperidine scaffold, makes it a valuable intermediate for constructing complex molecules with specific pharmacological or material properties. This compound is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, pain management, and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of novel pesticides, herbicides, and plant growth regulators where the piperidine moiety imparts specific biological activity.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing chiral ligands or metal-organic complexes used in asymmetric catalysis and coordination chemistry.
• Polymer Modification: Functional monomer for introducing polar, hydrogen-bonding groups into polymers to modify solubility, adhesion, or biocompatibility properties.
• Chemical Research & Development: Essential tool compound in academic and industrial R&D labs for exploring new synthetic methodologies and constructing heterocyclic libraries.
• Bioconjugation Linker: Potential use in bioconjugation chemistry for attaching payloads to biomolecules, leveraging its carboxylic acid group for amide bond formation.

Basic Information

Product Name	2-(2-(Hydroxymethyl)Piperidin-1-Yl)Acetic Acid
CAS No.	1228821-98-4
Molecular Formula	C8H15NO3
Molecular Weight	173.21 g/mol
Synonyms	1-(Carboxymethyl)-2-piperidinemethanol; 2-(Hydroxymethyl)-1-piperidineacetic Acid; 2-Piperidinemethanol, 1-(carboxymethyl)-; 1-Piperidineacetic acid, 2-(hydroxymethyl)-; (2-(Hydroxymethyl)piperidin-1-yl)acetic acid; 2-(2-Hydroxymethyl-piperidin-1-yl)-acetic acid; NSC 405124; 1228821-98-4
EINECS	Contact for details

Quality Control

Our 2-(2-(Hydroxymethyl)Piperidin-1-Yl)Acetic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-compliant development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.