Description

2-(3-((tert-Butyldimethylsilyloxy)Methyl)-Pyrrolidin-1-Yl)-6-(Pyrrolidin-1-Yl)Pyridine is a high-value, synthetically advanced chemical intermediate featuring a pyridine core with dual pyrrolidine and silyl-protected functional groups. This compound is critical for pharmaceutical research and development, particularly in the synthesis of complex bioactive molecules and active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to build sophisticated nitrogen-containing heterocyclic architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Ligand Precursor: Serves as a precursor for the development of specialized ligands in catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Used in the discovery and development of new herbicides and pesticides with complex mode-of-action profiles.
• Chemical Biology Probe Synthesis: Employed to create tool compounds for studying biological pathways and protein function.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for methodological development in organic synthesis.
• Process Chemistry: Investigated for scalable routes in the production of high-value fine chemicals under GMP-like conditions.

Basic Information

Product Name	2-(3-((tert-Butyldimethylsilyloxy)Methyl)-Pyrrolidin-1-Yl)-6-(Pyrrolidin-1-Yl)Pyridine
CAS No.	1228666-52-1
Molecular Formula	C20H35N3OSi
Molecular Weight	361.60 g/mol
Synonyms	2-[3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]-1-pyrrolidinyl]-6-(1-pyrrolidinyl)pyridine; 6-(Pyrrolidin-1-yl)-2-[3-[[(tert-butyldimethylsilyl)oxy]methyl]pyrrolidin-1-yl]pyridine; TBDMS-protected pyrrolidinylpyridine derivative; 2-(3-(TBDMS-oxymethyl)pyrrolidin-1-yl)-6-(pyrrolidin-1-yl)pyridine; 1228666-52-1; Pyrrolidinyl Pyridine Silyl Ether
EINECS	Contact for details

Quality Control

Our 2-(3-((tert-Butyldimethylsilyloxy)Methyl)-Pyrrolidin-1-Yl)-6-(Pyrrolidin-1-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.