Description

5-Fluoro-4-Methyl-1H-Pyrrolo[2,3-B]Pyridine is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique fused pyrrolopyridine core, functionalized with fluorine and methyl groups, makes it a critical intermediate for developing novel bioactive molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor programs and other targeted therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrrolopyridine scaffold.
• Material Science Precursor: Serves as a building block for creating specialized organic ligands and functional materials with tailored electronic properties.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies and the exploration of new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	5-Fluoro-4-Methyl-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1228666-30-5
Molecular Formula	C8H7FN2
Molecular Weight	150.16 g/mol
Synonyms	4-Methyl-5-fluoro-1H-pyrrolo[2,3-b]pyridine; 5-Fluoro-4-methyl-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 5-fluoro-4-methyl-; 4-Methyl-5-fluoropyrrolo[2,3-b]pyridine; 5-Fluoro-4-methylpyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Every batch of 5-Fluoro-4-Methyl-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.