Description

2,3-Dihydro-1H-Pyrido[3,4-B][1,4]Oxazine-8-Carbonitrile is a high-value nitrogen-containing heterocyclic compound, specifically a fused bicyclic carbonitrile. This advanced pharmaceutical intermediate is critical for research and development in medicinal chemistry, offering a versatile scaffold for constructing complex bioactive molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Organic Synthesis Reagent: Serves as a precursor for further functionalization, enabling the creation of diverse chemical entities through reactions at the nitrile and heterocyclic moieties.
• Agrochemical Development: Potential intermediate in the research and synthesis of novel active ingredients for crop protection products.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and functional materials with specific electronic or binding properties.

Basic Information

Product Name	2,3-Dihydro-1H-Pyrido[3,4-B][1,4]Oxazine-8-Carbonitrile
CAS No.	1228666-02-1
Molecular Formula	C9H7N3O
Molecular Weight	173.17 g/mol
Synonyms	8-Cyano-2,3-dihydro-1H-pyrido[3,4-b][1,4]oxazine; 1H-Pyrido[3,4-b][1,4]oxazine-8-carbonitrile, 2,3-dihydro-; 2,3-Dihydro-1H-pyrido[3,4-b][1,4]oxazine-8-carbonitrile; Pyrido[3,4-b][1,4]oxazine-8-carbonitrile, 2,3-dihydro-1H-; 1228666-02-1
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-1H-Pyrido[3,4-B][1,4]Oxazine-8-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.