Description

Methyl 3-(2-Amino-5-Fluoropyridin-3-Yl)Propanoate is a high-value fluorinated pyridine derivative, serving as a critical building block in modern synthetic organic chemistry. This compound is essential for the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals due to its unique structural motifs. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in oncology, central nervous system (CNS), and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that benefit from the stability and bioavailability imparted by the fluoropyridine core.
• Chemical Research & Development: Serves as a versatile precursor in medicinal chemistry and process chemistry for introducing the 2-amino-5-fluoropyridine moiety into target molecules.
• Ligand and Catalyst Development: Potential utility in the design of novel ligands for catalysis or as a scaffold in material science applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and clinical trial materials.

Basic Information

Product Name	Methyl 3-(2-Amino-5-Fluoropyridin-3-Yl)Propanoate
CAS No.	1228665-99-3
Molecular Formula	C9H11FN2O2
Molecular Weight	198.20 g/mol
Synonyms	3-(2-Amino-5-fluoro-3-pyridinyl)propanoic acid methyl ester; Methyl 3-(2-amino-5-fluoropyridin-3-yl)propionate; 2-Amino-5-fluoro-3-pyridinepropanoic acid methyl ester; 1228665-99-3; Methyl β-(2-amino-5-fluoropyridin-3-yl)propanoate; 3-Pyridinepropanoic acid, 2-amino-5-fluoro-, methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-(2-Amino-5-Fluoropyridin-3-Yl)Propanoate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is manufactured under controlled conditions and analyzed using advanced techniques such as HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, supporting cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.