Description

1-Pivaloyl-2,3-Dihydro-1H-Pyrido[2,3-B][1,4]-Oxazine-6-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, especially for central nervous system (CNS) and anti-infective research.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing novel pyrido-oxazine-based heterocyclic libraries.
• Medicinal Chemistry: Serves as a crucial precursor for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the cGMP production of clinical trial materials.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	1-Pivaloyl-2,3-Dihydro-1H-Pyrido[2,3-B][1,4]-Oxazine-6-Carboxylic Acid
CAS No.	1228665-93-7
Molecular Formula	C15H18N2O4
Molecular Weight	290.32 g/mol
Synonyms	1-Pivaloyl-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazine-6-carboxylic acid; 2,3-Dihydro-1-(2,2-dimethylpropanoyl)-1H-pyrido[2,3-b][1,4]oxazine-6-carboxylic acid; 1H-Pyrido[2,3-b][1,4]oxazine-6-carboxylic acid, 2,3-dihydro-1-(2,2-dimethyl-1-oxopropoxy)-; Pivaloyl DHPO-6-carboxylic Acid; CAS 1228665-93-7
EINECS	Contact for details

Quality Control

Our 1-Pivaloyl-2,3-Dihydro-1H-Pyrido[2,3-B][1,4]-Oxazine-6-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled and stored away from strong light sources. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.