Description

4-Chloro-5-Fluoro-6-Iodo-1H-Pyrrolo[2,3-B]Pyridine is a highly functionalized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because its unique halogenated pyrrolopyridine core is a critical intermediate for constructing complex molecules with tailored biological activity. It is primarily needed by pharmaceutical and agrochemical research organizations for the development of new active ingredients, particularly kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: A key scaffold in the synthesis of novel kinase inhibitors for oncology and inflammatory disease research.
• Agrochemical Development: Used as a building block for creating new active ingredients with potential herbicidal or fungicidal properties.
• Chemical Biology Probe Synthesis: Serves as a versatile precursor for labeling molecules or creating tool compounds to study biological pathways.
• Material Science Research: Potential precursor for organic electronic materials due to its electron-deficient fused-ring system.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and cross-coupling chemistry.

Basic Information

Product Name	4-Chloro-5-Fluoro-6-Iodo-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1228665-91-5
Molecular Formula	C7H2ClFIN2
Molecular Weight	310.46 g/mol
Synonyms	4-Chloro-5-fluoro-6-iodo-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-5-fluoro-6-iodo-; 4-Chloro-5-fluoro-6-iodo-7-azaindole; 6-Iodo-4-chloro-5-fluoro-1H-pyrrolo[2,3-b]pyridine; 4-Chloro-5-fluoro-6-iodopyrrolo[2,3-b]pyridine; 1228665-91-5; 4-Cl-5-F-6-I-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Fluoro-6-Iodo-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.