Description

1-Pivaloyl-2,3-Dihydro-1H-Pyrido[2,3-B][1,4]-Oxazine-6-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused heterocyclic structure. This compound is of significant value in medicinal chemistry for the synthesis of novel drug candidates, particularly those targeting central nervous system disorders. It is primarily utilized by research institutions and pharmaceutical development companies engaged in the creation of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new active pharmaceutical ingredients (APIs), especially for neurological targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Organic Synthesis: Serves as a versatile precursor for constructing complex nitrogen- and oxygen-containing heterocyclic scaffolds.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of novel chemical entities.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	1-Pivaloyl-2,3-Dihydro-1H-Pyrido[2,3-B][1,4]-Oxazine-6-Carbaldehyde
CAS No.	1228665-85-7
Molecular Formula	C13H16N2O3
Molecular Weight	248.28 g/mol
Synonyms	1-Pivaloyl-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazine-6-carboxaldehyde; 6-Formyl-1-pivaloyl-1,2,3,4-tetrahydropyrido[2,3-b][1,4]oxazine; 1-(2,2-Dimethylpropanoyl)-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazine-6-carbaldehyde; Pyrido[2,3-b][1,4]oxazine-6-carbaldehyde, 1-(2,2-dimethyl-1-oxopropyl)-2,3-dihydro-; 1228665-85-7
EINECS	Contact for details

Quality Control

Our 1-Pivaloyl-2,3-Dihydro-1H-Pyrido[2,3-B][1,4]-Oxazine-6-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.