Description

(S)-Amino-Pyridin-4-Yl-Acetic Acid CAS NO 1228559-23-6 is a high-purity chiral building block and pharmaceutical intermediate characterized by its pyridine and amino acid functional groups. Its primary value lies in enabling the synthesis of enantiomerically pure compounds, which is critical for developing active pharmaceutical ingredients (APIs) with high specificity and reduced side effects. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require a reliable source of high-quality, stereochemically defined intermediates.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel small-molecule drugs, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Asymmetric Synthesis: Serves as a versatile building block in catalytic asymmetric reactions to construct complex molecular architectures.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for metal-catalyzed transformations and organocatalysts.
• Agrochemical Research: Intermediate in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Peptidomimetics & Bio-conjugates: Incorporation into peptide backbones to create stable analogs or for bioconjugation strategies in drug delivery systems.
• Academic & Process Chemistry: A valuable reagent for methodological studies in organic synthesis and for scaling up synthetic routes under GMP-like conditions.

Basic Information

Item	Details
Product Name	(S)-Amino-Pyridin-4-Yl-Acetic Acid
CAS No.	1228559-23-6
Molecular Formula	C7H8N2O2
Molecular Weight	152.15 g/mol
Synonyms	(S)-2-Amino-2-(pyridin-4-yl)acetic acid; (S)-4-Pyridylglycine; (S)-Amino(4-pyridyl)acetic acid; L-4-Pyridylglycine; (S)-α-Amino-4-pyridineacetic acid; (2S)-2-Amino-2-(4-pyridinyl)acetic acid; (S)-2-(4-Pyridinyl)glycine
EINECS	Contact for details

Quality Control

Our (S)-Amino-Pyridin-4-Yl-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.