Description

(S)-2-o-Tolylpiperidine is a chiral piperidine derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a valuable building block and intermediate for the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly those targeting neurological and central nervous system disorders.
• Asymmetric Synthesis: Employed as a chiral ligand or auxiliary in catalytic asymmetric reactions to induce stereoselectivity.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its structural motif for biological activity.
• Chemical Biology: Serves as a probe or scaffold in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Material Science: Potential intermediate for the synthesis of advanced organic materials and liquid crystals.

Basic Information

Product Name	(S)-2-o-Tolylpiperidine
CAS No.	1228547-99-6
Molecular Formula	C12H17N
Molecular Weight	175.27 g/mol
Synonyms	(S)-2-(2-Methylphenyl)piperidine; (S)-2-(o-Tolyl)piperidine; (S)-2-(2-Methylphenyl)piperidine; (S)-α-Methyl-2-piperidinobenzyl alcohol (tautomer); (S)-2-(2-Methylphenyl)piperidine; (S)-2-o-Tolyl-piperidine; (S)-2-(2-Methylphenyl)piperidine; (S)-2-(2-Methylphenyl)piperidine
EINECS	Contact for details

Quality Control

Our (S)-2-o-Tolylpiperidine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and enantiomeric purity suitable for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.