Description

6-Cyclobutylnicotinic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique cyclobutyl-substituted pyridinecarboxylic acid structure. This compound is of significant value in modern medicinal chemistry for its role as a versatile building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within the fields of oncology, neurology, and metabolic disease research.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted small-molecule therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Chemical Synthesis: Serves as a precursor for the preparation of more complex heterocyclic compounds and functionalized nicotinic acid derivatives.
• Agrochemical Development: Potential application in the research and synthesis of new crop protection agents with specific biological activity.
• Material Science: Can be investigated as a monomer or ligand for constructing functional polymers or metal-organic frameworks (MOFs).

Basic Information

Product Name	6-Cyclobutylnicotinic Acid
CAS No.	1228112-80-8
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	6-Cyclobutylpyridine-3-carboxylic Acid; 3-Pyridinecarboxylic acid, 6-cyclobutyl-; Nicotinic acid, 6-cyclobutyl-; 6-Cyclobutyl-3-pyridinecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 6-Cyclobutylnicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications in cGMP and non-GMP pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.