Description

2-Bromo-5-Fluoro-3-Nitropyridin-4-Amine is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique halogenated and nitrated pyridine core makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its bioactive pyridine scaffold.
• Material Science: Serves as a building block for creating specialized ligands, polymers, and liquid crystals.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce complex functionalities.
• Academic & Contract Research: Essential for medicinal chemistry programs and process research in academic and CRO (Contract Research Organization) settings.

Basic Information

Product Name	2-Bromo-5-Fluoro-3-Nitropyridin-4-Amine
CAS No.	1227958-53-3
Molecular Formula	C5H3BrFN3O2
Molecular Weight	235.99 g/mol
Synonyms	4-Amino-2-bromo-5-fluoro-3-nitropyridine; 2-Bromo-5-fluoro-3-nitro-4-pyridinamine; 4-Pyridinamine, 2-bromo-5-fluoro-3-nitro-; 1227958-53-3; 2-Bromo-5-fluoro-3-nitropyridin-4-ylamine
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Fluoro-3-Nitropyridin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.